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neutrophil cytosolic factor 1 : ウィキペディア英語版 | neutrophil cytosolic factor 1
Neutrophil cytosol factor 1 is a protein that in humans is encoded by the ''NCF1'' gene. == Function ==
The protein encoded by this gene is a 47 kDa cytosolic subunit of neutrophil NADPH oxidase. This oxidase is a multicomponent enzyme that is activated to produce superoxide anion. Mutations in this gene have been associated with chronic granulomatous disease.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=653361 )〕 p47 is vital to the activation of NADPH oxidase. P47 becomes heavily phosphorylated
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